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Laurie Sutton

Assistant Professor

Biological Sciences

ILSB 318


Ph D University of Western Ontario 2011

MS University of Western Ontario 2005

BS University of Waterloo 2003


I received my BS in Biochemistry from the University of Waterloo. My PhD was obtained from the University of Western Ontario in the Cell Biology department. I conducted my postdoctoral work in the laboratories of Drs. Marc Caron at Duke University and Kirill Martemyanov at The Scripps Research Institute (Neuroscience department).

Research Interests

My research interest focuses on understanding the behavioral and physiological role of a group of understudied proteins called orphan receptors.

Teaching Interests

Cell biology, Neuroscience

Intellectual Contributions

Sutton, Laurie, Muntean, B S., Ostrovskaya, O, Zucca, S, Dao, M, Orlandi, C, Song, C, Xie, K, Martemyanov, K A. (2019). NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control.. 10. 17 e3000477 PLoS biology.

Song, C, Orlandi, C, Sutton, Laurie, Martemyanov, K A. (2019). The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex.. 35. 294 13145-13157 The Journal of biological chemistry.

Orlandi, C, Sutton, Laurie, Muntean, B S., Song, C, Martemyanov, K A. (2019). Homeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors.. 3. 44 642-653 Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Sutton, Laurie, Orlandi, C, Song, C, Oh, W C., Muntean, B S., Xie, K, Filippini, A, Xie, X, Satterfield, R, Renner, K J., Young, Jr, S M., Xu, B, Kwon, H, Martemyanov, K A. (2018). Orphan receptor GPR158 controls stress-induced depression.. 7 eLife.

Xie, K, Colgan, L A., Dao, M T., Muntean, B S., Sutton, Laurie, Orlandi, C, Boye, S L., Boye, S E., Shih, C C., Li, Y, Xu, B, Smith, R G., Yasuda, R, Martemyanov, K A. (2016). NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum.. 22. 26 2992-3003 Current biology : CB.

Sutton, Laurie, Ostrovskaya, O, Dao, M, Xie, K, Orlandi, C, Smith, R, Wee, S, Martemyanov, K A. (2016). Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum.. 3. 80 235-45 Biological psychiatry.

Sutton, Laurie, Caron, M G. (2015). Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine.. 99 610-9 Neuropharmacology.