I received my BS in Biochemistry from the University of Waterloo. My PhD was obtained from the University of Western Ontario in the Cell Biology department. I conducted my postdoctoral work in the laboratory of Dr. Martemyanov at The Scripps Research Institute (Neuroscience department).
My research interest focuses on understanding the behavioral and physiological role of a group of understudied proteins called orphan receptors.
Cell biology, Neuroscience
(2019) NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control. PLoS biology
(2019) The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex. The Journal of biological chemistry
(2019) Homeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
(2018) Orphan receptor GPR158 controls stress-induced depression. eLife
(2016) NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum. Current biology : CB
(2016) Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum. Biological psychiatry
(2015) Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine. Neuropharmacology