Laurie Sutton
Assistant Professor
Biological Sciences
ILSB 318
Education
Ph D University of Western Ontario 2011
MS University of Western Ontario 2005
BS University of Waterloo 2003
About
I received my BS in Biochemistry from the University of Waterloo. My PhD was obtained from the University of Western Ontario in the Cell Biology department. I conducted my postdoctoral work in the laboratories of Drs. Marc Caron at Duke University and Kirill Martemyanov at The Scripps Research Institute (Neuroscience department).
Research Interests
My research interest focuses on understanding the behavioral and physiological role of a group of understudied proteins called orphan receptors.
Teaching Interests
Cell biology, Neuroscience
Intellectual Contributions
Sutton, Laurie, Muntean, B S., Ostrovskaya, O, Zucca, S, Dao, M, Orlandi, C, Song, C, Xie, K, Martemyanov, K A. (2019). NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control.. 10. 17 e3000477 PLoS biology.
Song, C, Orlandi, C, Sutton, Laurie, Martemyanov, K A. (2019). The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex.. 35. 294 13145-13157 The Journal of biological chemistry.
Orlandi, C, Sutton, Laurie, Muntean, B S., Song, C, Martemyanov, K A. (2019). Homeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors.. 3. 44 642-653 Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
Sutton, Laurie, Orlandi, C, Song, C, Oh, W C., Muntean, B S., Xie, K, Filippini, A, Xie, X, Satterfield, R, Renner, K J., Young, Jr, S M., Xu, B, Kwon, H, Martemyanov, K A. (2018). Orphan receptor GPR158 controls stress-induced depression.. 7 eLife.
Xie, K, Colgan, L A., Dao, M T., Muntean, B S., Sutton, Laurie, Orlandi, C, Boye, S L., Boye, S E., Shih, C C., Li, Y, Xu, B, Smith, R G., Yasuda, R, Martemyanov, K A. (2016). NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum.. 22. 26 2992-3003 Current biology : CB.
Sutton, Laurie, Ostrovskaya, O, Dao, M, Xie, K, Orlandi, C, Smith, R, Wee, S, Martemyanov, K A. (2016). Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum.. 3. 80 235-45 Biological psychiatry.
Sutton, Laurie, Caron, M G. (2015). Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine.. 99 610-9 Neuropharmacology.